CHD8 mutations increase gliogenesis to enlarge brain size in the nonhuman primate

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition that affects social interaction and behavior. Mutations in the gene encoding chromodomain helicase DNA-binding protein 8 (CHD8) lead to autism symptoms and macrocephaly by a haploinsufficiency mechanism. However, studies of sma...

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Detalles Bibliográficos
Autores principales: Li, Bang, Zhao, Hui, Tu, Zhuchi, Yang, Weili, Han, Rui, Wang, Lu, Luo, Xiaopeng, Pan, Mingtian, Chen, Xiusheng, Zhang, Jiawei, Xu, Huijuan, Guo, Xiangyu, Yan, Sen, Yin, Peng, Zhao, Zhiguang, Liu, Jianrong, Luo, Yafeng, Li, Yuefeng, Yang, Zhengyi, Zhang, Baogui, Tan, Zhiqiang, Xu, Hao, Jiang, Tianzi, Jiang, Yong-hui, Li, Shihua, Zhang, Yong Q., Li, Xiao-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988832/
https://www.ncbi.nlm.nih.gov/pubmed/36878905
http://dx.doi.org/10.1038/s41421-023-00525-3

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