Cargando…
Effects of fermented soybean meal supplementation on the growth performance and apparent total tract digestibility by modulating the gut microbiome of weaned piglets
This study investigates the effects of soybean meal fermented by Enterococcus faecium as a replacement for soybean meal on growth performance, apparent total tract digestibility, blood profile and gut microbiota of weaned pigs. Eighty piglets (weaned at 21 days) [(Landrace × Yorkshire) × Duroc] with...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988856/ https://www.ncbi.nlm.nih.gov/pubmed/36878925 http://dx.doi.org/10.1038/s41598-023-30698-6 |
_version_ | 1784901656811405312 |
---|---|
author | Muniyappan, Madesh Shanmugam, Sureshkumar Park, Jae Hong Han, Kyudong Kim, In Ho |
author_facet | Muniyappan, Madesh Shanmugam, Sureshkumar Park, Jae Hong Han, Kyudong Kim, In Ho |
author_sort | Muniyappan, Madesh |
collection | PubMed |
description | This study investigates the effects of soybean meal fermented by Enterococcus faecium as a replacement for soybean meal on growth performance, apparent total tract digestibility, blood profile and gut microbiota of weaned pigs. Eighty piglets (weaned at 21 days) [(Landrace × Yorkshire) × Duroc] with average body weight of 6.52 ± 0.59 kg) were selected and assigned to 4 treatments/4 replicate pens (3 barrows and 2 gilts). The four diets (SBM, 3, 6 and 9% FSBM) were formulated using fermented soybean meal to replace 0, 3, 6 and 9% of soybean meal, respectively. The trial lasted for 42 days phase 1, 2 and 3. Result showed that supplemental FSBM increased (P < 0.05) the body weight gain (BWG) of piglets at day 7, 21 and 42 and ADG at days 1–7, 8–21, 22–42 and 1–42, and ADFI at days 8–21, 22–42 and 1–42 and G: F at days 1–7, 8–21 and 1–42, and crude protein, dry matter, and gross energy digestibility at day 42, and lowered (P < 0.05) diarrhea at days 1–21 and 22–42. The concentration of glucose levels, WBC, RBC, and lymphocytes were increased while, concentration of BUN level in the serum was lowered in the FSBM treatment compared to the SBM group (P < 0.05). Microbiota sequencing found that FSBM supplementation increased the microbial Shannon, Simpsons and Chao indexs, (P < 0.05) and the abundances of the phylum Firmicutes, and genera prevotella, Lactobacillus, Lachnospiraceae and Lachnoclostridium (P < 0.05), lower in the abundances of the phylum bacteroidetes, Proteobacteria, genera Escherichia-Shigella, Clostridium sensu stricto1, Bacteroides and Parabacteroides (P < 0.05). Overall, FSBM replacing SBM improved the growth performance, apparent total tract digestibility, and blood profiles; perhaps via altering the faecal microbiota and its metabolites in weaned pigs. The present study provides theoretical support for applying FSBM at 6–9% to promote immune characteristics and regulate intestinal health in weaning piglets. |
format | Online Article Text |
id | pubmed-9988856 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-99888562023-03-08 Effects of fermented soybean meal supplementation on the growth performance and apparent total tract digestibility by modulating the gut microbiome of weaned piglets Muniyappan, Madesh Shanmugam, Sureshkumar Park, Jae Hong Han, Kyudong Kim, In Ho Sci Rep Article This study investigates the effects of soybean meal fermented by Enterococcus faecium as a replacement for soybean meal on growth performance, apparent total tract digestibility, blood profile and gut microbiota of weaned pigs. Eighty piglets (weaned at 21 days) [(Landrace × Yorkshire) × Duroc] with average body weight of 6.52 ± 0.59 kg) were selected and assigned to 4 treatments/4 replicate pens (3 barrows and 2 gilts). The four diets (SBM, 3, 6 and 9% FSBM) were formulated using fermented soybean meal to replace 0, 3, 6 and 9% of soybean meal, respectively. The trial lasted for 42 days phase 1, 2 and 3. Result showed that supplemental FSBM increased (P < 0.05) the body weight gain (BWG) of piglets at day 7, 21 and 42 and ADG at days 1–7, 8–21, 22–42 and 1–42, and ADFI at days 8–21, 22–42 and 1–42 and G: F at days 1–7, 8–21 and 1–42, and crude protein, dry matter, and gross energy digestibility at day 42, and lowered (P < 0.05) diarrhea at days 1–21 and 22–42. The concentration of glucose levels, WBC, RBC, and lymphocytes were increased while, concentration of BUN level in the serum was lowered in the FSBM treatment compared to the SBM group (P < 0.05). Microbiota sequencing found that FSBM supplementation increased the microbial Shannon, Simpsons and Chao indexs, (P < 0.05) and the abundances of the phylum Firmicutes, and genera prevotella, Lactobacillus, Lachnospiraceae and Lachnoclostridium (P < 0.05), lower in the abundances of the phylum bacteroidetes, Proteobacteria, genera Escherichia-Shigella, Clostridium sensu stricto1, Bacteroides and Parabacteroides (P < 0.05). Overall, FSBM replacing SBM improved the growth performance, apparent total tract digestibility, and blood profiles; perhaps via altering the faecal microbiota and its metabolites in weaned pigs. The present study provides theoretical support for applying FSBM at 6–9% to promote immune characteristics and regulate intestinal health in weaning piglets. Nature Publishing Group UK 2023-03-06 /pmc/articles/PMC9988856/ /pubmed/36878925 http://dx.doi.org/10.1038/s41598-023-30698-6 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Muniyappan, Madesh Shanmugam, Sureshkumar Park, Jae Hong Han, Kyudong Kim, In Ho Effects of fermented soybean meal supplementation on the growth performance and apparent total tract digestibility by modulating the gut microbiome of weaned piglets |
title | Effects of fermented soybean meal supplementation on the growth performance and apparent total tract digestibility by modulating the gut microbiome of weaned piglets |
title_full | Effects of fermented soybean meal supplementation on the growth performance and apparent total tract digestibility by modulating the gut microbiome of weaned piglets |
title_fullStr | Effects of fermented soybean meal supplementation on the growth performance and apparent total tract digestibility by modulating the gut microbiome of weaned piglets |
title_full_unstemmed | Effects of fermented soybean meal supplementation on the growth performance and apparent total tract digestibility by modulating the gut microbiome of weaned piglets |
title_short | Effects of fermented soybean meal supplementation on the growth performance and apparent total tract digestibility by modulating the gut microbiome of weaned piglets |
title_sort | effects of fermented soybean meal supplementation on the growth performance and apparent total tract digestibility by modulating the gut microbiome of weaned piglets |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988856/ https://www.ncbi.nlm.nih.gov/pubmed/36878925 http://dx.doi.org/10.1038/s41598-023-30698-6 |
work_keys_str_mv | AT muniyappanmadesh effectsoffermentedsoybeanmealsupplementationonthegrowthperformanceandapparenttotaltractdigestibilitybymodulatingthegutmicrobiomeofweanedpiglets AT shanmugamsureshkumar effectsoffermentedsoybeanmealsupplementationonthegrowthperformanceandapparenttotaltractdigestibilitybymodulatingthegutmicrobiomeofweanedpiglets AT parkjaehong effectsoffermentedsoybeanmealsupplementationonthegrowthperformanceandapparenttotaltractdigestibilitybymodulatingthegutmicrobiomeofweanedpiglets AT hankyudong effectsoffermentedsoybeanmealsupplementationonthegrowthperformanceandapparenttotaltractdigestibilitybymodulatingthegutmicrobiomeofweanedpiglets AT kiminho effectsoffermentedsoybeanmealsupplementationonthegrowthperformanceandapparenttotaltractdigestibilitybymodulatingthegutmicrobiomeofweanedpiglets |