CRISPR/Cas9 mediated specific ablation of vegfa in retinal pigment epithelium efficiently regresses choroidal neovascularization

The CRISPR/Cas9 system easily edits target genes in various organisms and is used to treat human diseases. In most therapeutic CRISPR studies, ubiquitously expressed promoters, such as CMV, CAG, and EF1α, are used; however, gene editing is sometimes necessary only in specific cell types relevant to...

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Detalles Bibliográficos
Autores principales: Park, Jinkyu, Cui, Gang, Lee, Hyundong, Jeong, Han, Kwak, Jay Jiyong, Lee, Junwon, Byeon, Suk Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988861/
https://www.ncbi.nlm.nih.gov/pubmed/36878916
http://dx.doi.org/10.1038/s41598-023-29014-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988861/
https://www.ncbi.nlm.nih.gov/pubmed/36878916
http://dx.doi.org/10.1038/s41598-023-29014-z

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