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USP7- and PRMT5-dependent G3BP2 stabilization drives de novo lipogenesis and tumorigenesis of HNSC

GTPase-activating protein-binding protein 2 (G3BP2) is a key stress granule-associated RNA-binding protein responsible for the formation of stress granules (SGs). Hyperactivation of G3BP2 is associated with various pathological conditions, especially cancers. Emerging evidence indicates that post-tr...

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Detalles Bibliográficos
Autores principales: Wang, Nan, Li, Tianzi, Liu, Wanyu, Lin, Jinhua, Zhang, Ke, Li, Zhenhao, Huang, Yanfei, Shi, Yufei, Xu, Meilan, Liu, Xuekui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988876/
https://www.ncbi.nlm.nih.gov/pubmed/36878903
http://dx.doi.org/10.1038/s41419-023-05706-2