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Mucociliary Wnt signaling promotes cilia biogenesis and beating

It is widely thought that Wnt/Lrp6 signaling proceeds through the cytoplasm and that motile cilia are signaling-inert nanomotors. Contrasting both views, we here show in the mucociliary epidermis of X. tropicalis embryos that motile cilia transduce a ciliary Wnt signal that is distinct from canonica...

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Detalles Bibliográficos
Autores principales: Seidl, Carina, Da Silva, Fabio, Zhang, Kaiqing, Wohlgemuth, Kai, Omran, Heymut, Niehrs, Christof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988884/
https://www.ncbi.nlm.nih.gov/pubmed/36878953
http://dx.doi.org/10.1038/s41467-023-36743-2

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