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Indoxyl sulfate induces left ventricular hypertrophy via the AhR-FGF23-FGFR4 signaling pathway

BACKGROUND: Patients with chronic kidney disease (CKD) have a high risk of left ventricular hypertrophy (LVH). Fibroblast growth factor 23 (FGF23) and indoxyl sulfate (IS) are associated with LVH in patients with CKD, but the interactions between these molecules remain unknown. We investigated wheth...

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Detalles Bibliográficos
Autores principales:	Kishimoto, Hiroshi, Nakano, Toshiaki, Torisu, Kumiko, Tokumoto, Masanori, Uchida, Yushi, Yamada, Shunsuke, Taniguchi, Masatomo, Kitazono, Takanari
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988908/ https://www.ncbi.nlm.nih.gov/pubmed/36895836 http://dx.doi.org/10.3389/fcvm.2023.990422

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