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The effect of Abi3 locus deletion on the progression of Alzheimer’s disease-related pathologies

Human genetics studies of Alzheimer’s disease (AD) have identified the ABI3 gene as a candidate risk gene for AD. Because ABI3 is highly expressed in microglia, the brain’s immune cells, it was suggested that ABI3 might impact AD pathogenesis by regulating the immune response. Recent studies suggest...

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Detalles Bibliográficos
Autores principales: Karahan, Hande, Smith, Daniel C., Kim, Byungwook, McCord, Brianne, Mantor, Jordan, John, Sutha K., Al-Amin, Md Mamun, Dabin, Luke C., Kim, Jungsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988916/
https://www.ncbi.nlm.nih.gov/pubmed/36895556
http://dx.doi.org/10.3389/fimmu.2023.1102530