Cargando…
Requirement for ER-mitochondria Ca(2+) transfer, ROS production and mPTP formation in L-asparaginase-induced apoptosis of acute lymphoblastic leukemia cells
Acute lymphoblastic leukemia (aLL) is a malignant cancer in the blood and bone marrow characterized by rapid expansion of lymphoblasts. It is a common pediatric cancer and the principal basis of cancer death in children. Previously, we reported that L-asparaginase, a key component of acute lymphobla...
Autores principales: | Lee, Jung Kwon, Rosales, Jesusa L., Lee, Ki-Young |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988955/ https://www.ncbi.nlm.nih.gov/pubmed/36895789 http://dx.doi.org/10.3389/fcell.2023.1124164 |
Ejemplares similares
-
mPTP opening caused by Cdk5 loss is due to increased mitochondrial Ca(2+) uptake
por: NavaneethaKrishnan, Saranya, et al.
Publicado: (2020) -
OPA1 Modulates Mitochondrial Ca(2+) Uptake Through ER-Mitochondria Coupling
por: Cartes-Saavedra, Benjamín, et al.
Publicado: (2022) -
Calcium Elevation in Mitochondria Is the Main Ca(2+) Requirement for Mitochondrial Permeability Transition Pore (mPTP) Opening
por: Baumgartner, Heidi K., et al.
Publicado: (2009) -
ER-mitochondria contact sites; a multifaceted factory for Ca(2+) signaling and lipid transport
por: Sassano, Maria Livia, et al.
Publicado: (2022) -
Extracellular acidification induces ROS- and mPTP-mediated death in HEK293 cells
por: Teixeira, José, et al.
Publicado: (2017)