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The TRPM7 channel reprograms cellular glycolysis to drive tumorigenesis and angiogenesis

Cancer or endothelial cells preferably catabolize glucose through aerobic glycolysis rather than oxidative phosphorylation. Intracellular ionic signaling has been shown to regulate glucose metabolism, but the underlying ion channel has yet to be identified. RNA-seq, metabolomics and genetic assay re...

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Detalles Bibliográficos
Autores principales: Wu, Wanzhou, Wang, Xuan, Liao, Longsheng, Chen, Jing, Wang, Yue, Yao, Meilian, Zhu, Lingping, Li, Jiayu, Chen, Alex F., Zhang, Guogang, Zhang, Zheng, Bai, Yongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988972/
https://www.ncbi.nlm.nih.gov/pubmed/36878949
http://dx.doi.org/10.1038/s41419-023-05701-7

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