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The TRPM7 channel reprograms cellular glycolysis to drive tumorigenesis and angiogenesis
Cancer or endothelial cells preferably catabolize glucose through aerobic glycolysis rather than oxidative phosphorylation. Intracellular ionic signaling has been shown to regulate glucose metabolism, but the underlying ion channel has yet to be identified. RNA-seq, metabolomics and genetic assay re...
Autores principales: | Wu, Wanzhou, Wang, Xuan, Liao, Longsheng, Chen, Jing, Wang, Yue, Yao, Meilian, Zhu, Lingping, Li, Jiayu, Chen, Alex F., Zhang, Guogang, Zhang, Zheng, Bai, Yongping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988972/ https://www.ncbi.nlm.nih.gov/pubmed/36878949 http://dx.doi.org/10.1038/s41419-023-05701-7 |
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