Protein adduction causes non-mutational inhibition of p53 tumor suppressor

p53 is a key tumor suppressor that is frequently mutated in human tumors. In this study, we investigated how p53 is regulated in precancerous lesions prior to mutations in the p53 gene. Analyzing esophageal cells in conditions of genotoxic stress that promotes development of esophageal adenocarcinom...

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Detalles Bibliográficos
Autores principales: Gokulan, Ravindran Caspa, Paulrasu, Kodisundaram, Azfar, Jamal, El-Rifai, Wael, Que, Jianwen, Boutaud, Olivier G., Ban, Yuguang, Gao, Zhen, Buitrago, Monica Garcia, Dikalov, Sergey I., Zaika, Alexander I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9989503/
https://www.ncbi.nlm.nih.gov/pubmed/36848235
http://dx.doi.org/10.1016/j.celrep.2023.112024

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