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The cryo‐EM structure of full‐length RAD52 protein contains an undecameric ring

The human RAD52 protein, which forms an oligomeric ring structure, is involved in DNA double‐strand break repair. The N‐terminal half of RAD52 is primarily responsible for self‐oligomerisation and DNA binding. Crystallographic studies have revealed the detailed structure of the N‐terminal half. Howe...

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Detalles Bibliográficos
Autores principales: Kinoshita, Chiaki, Takizawa, Yoshimasa, Saotome, Mika, Ogino, Shun, Kurumizaka, Hitoshi, Kagawa, Wataru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9989933/
https://www.ncbi.nlm.nih.gov/pubmed/36707939
http://dx.doi.org/10.1002/2211-5463.13565