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Direct intranodal tonsil vaccination with modified vaccinia Ankara vaccine protects macaques from highly pathogenic SIVmac251

Human immunodeficiency virus (HIV) is a mucosally transmitted virus that causes immunodeficiency and AIDS. Developing efficacious vaccines to prevent infection is essential to control the epidemic. Protecting the vaginal and rectal mucosa, the primary routes of HIV entry has been a challenge given t...

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Detalles Bibliográficos
Autores principales: Mattathil, Jeffy G., Volz, Asisa, Onabajo, Olusegun O., Maynard, Sean, Bixler, Sandra L., Shen, Xiaoying X., Vargas-Inchaustegui, Diego, Robert-Guroff, Marjorie, Lebranche, Celia, Tomaras, Georgia, Montefiori, David, Sutter, Gerd, Mattapallil, Joseph J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990026/
https://www.ncbi.nlm.nih.gov/pubmed/36882405
http://dx.doi.org/10.1038/s41467-023-36907-0