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A case of severe paraquat poisoning treated by continuous hemodiafiltration without sequelae
BACKGROUND: In a suicide attempt, a 49‐year‐old male ingested pesticides. He arrived at the hospital restless and vomiting blue liquid. CASE PRESENTATION: The patient was diagnosed with paraquat poisoning at a lethal dose and experienced renal dysfunction during treatment. He underwent continuous he...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990155/ https://www.ncbi.nlm.nih.gov/pubmed/36895322 http://dx.doi.org/10.1002/ams2.833 |
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author | Hisamura, Masaki Ogura, Tomoyuki Tokuda, Mitsuhiro Nakamura, Motohiro Kenichiro, Sonoda Ando, Yoji Nakata, Kazuyuki Taguchi, Hirokazu |
author_facet | Hisamura, Masaki Ogura, Tomoyuki Tokuda, Mitsuhiro Nakamura, Motohiro Kenichiro, Sonoda Ando, Yoji Nakata, Kazuyuki Taguchi, Hirokazu |
author_sort | Hisamura, Masaki |
collection | PubMed |
description | BACKGROUND: In a suicide attempt, a 49‐year‐old male ingested pesticides. He arrived at the hospital restless and vomiting blue liquid. CASE PRESENTATION: The patient was diagnosed with paraquat poisoning at a lethal dose and experienced renal dysfunction during treatment. He underwent continuous hemodiafiltration (CHDF). Hemodialysis was temporarily initiated and found to improve renal function. He was discharged on day 36 in good condition. He remains well with only mild renal impairment and no pulmonary fibrosis, 240 days after the incident. The fatality rate of paraquat poisoning is approximately 80%, regardless of the treatment. Early hemodialysis combined with CHDF within 4 h has been reported to be effective. In this case, CHDF was initiated approximately 3 h after paraquat administration and showed a successful outcome. CONCLUSION: CHDF should be performed as soon as possible to treat paraquat poisoning. |
format | Online Article Text |
id | pubmed-9990155 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-99901552023-03-08 A case of severe paraquat poisoning treated by continuous hemodiafiltration without sequelae Hisamura, Masaki Ogura, Tomoyuki Tokuda, Mitsuhiro Nakamura, Motohiro Kenichiro, Sonoda Ando, Yoji Nakata, Kazuyuki Taguchi, Hirokazu Acute Med Surg Case Report BACKGROUND: In a suicide attempt, a 49‐year‐old male ingested pesticides. He arrived at the hospital restless and vomiting blue liquid. CASE PRESENTATION: The patient was diagnosed with paraquat poisoning at a lethal dose and experienced renal dysfunction during treatment. He underwent continuous hemodiafiltration (CHDF). Hemodialysis was temporarily initiated and found to improve renal function. He was discharged on day 36 in good condition. He remains well with only mild renal impairment and no pulmonary fibrosis, 240 days after the incident. The fatality rate of paraquat poisoning is approximately 80%, regardless of the treatment. Early hemodialysis combined with CHDF within 4 h has been reported to be effective. In this case, CHDF was initiated approximately 3 h after paraquat administration and showed a successful outcome. CONCLUSION: CHDF should be performed as soon as possible to treat paraquat poisoning. John Wiley and Sons Inc. 2023-03-07 /pmc/articles/PMC9990155/ /pubmed/36895322 http://dx.doi.org/10.1002/ams2.833 Text en © 2023 The Authors. Acute Medicine & Surgery published by John Wiley & Sons Australia, Ltd on behalf of Japanese Association for Acute Medicine. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Case Report Hisamura, Masaki Ogura, Tomoyuki Tokuda, Mitsuhiro Nakamura, Motohiro Kenichiro, Sonoda Ando, Yoji Nakata, Kazuyuki Taguchi, Hirokazu A case of severe paraquat poisoning treated by continuous hemodiafiltration without sequelae |
title | A case of severe paraquat poisoning treated by continuous hemodiafiltration without sequelae |
title_full | A case of severe paraquat poisoning treated by continuous hemodiafiltration without sequelae |
title_fullStr | A case of severe paraquat poisoning treated by continuous hemodiafiltration without sequelae |
title_full_unstemmed | A case of severe paraquat poisoning treated by continuous hemodiafiltration without sequelae |
title_short | A case of severe paraquat poisoning treated by continuous hemodiafiltration without sequelae |
title_sort | case of severe paraquat poisoning treated by continuous hemodiafiltration without sequelae |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990155/ https://www.ncbi.nlm.nih.gov/pubmed/36895322 http://dx.doi.org/10.1002/ams2.833 |
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