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Specific TCR profiles predict clinical outcome of adjuvant EGFR-TKIs for resected EGFR-mutant non-small cell lung cancer

BACKGROUND: ADJUVANT-CTONG1104 reported a favorable survival outcome from adjuvant gefitinib treatment over chemotherapy in EGFR-mutant non-small cell lung cancer (NSCLC) patients. However, heterogeneous benefit from EGFR-TKIs and chemotherapy demands further biomarker exploration for patient select...

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Detalles Bibliográficos
Autores principales: Liu, Si-Yang Maggie, Chen, Cunte, Zhang, Yi-Kai, Zhong, Wen-Zhao, Wu, Yi-Long, Liu, Si-Yang, Li, Yangqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990191/
https://www.ncbi.nlm.nih.gov/pubmed/36879350
http://dx.doi.org/10.1186/s40364-023-00470-z