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Metformin attenuates symptoms of osteoarthritis: role of genetic diversity of Bcl2 and CXCL16 in OA
OBJECTIVE: This study aimed to evaluate the effectiveness of metformin versus placebo in overweight patients with knee osteoarthritis (OA). In addition, to assess the effects of inflammatory mediators and apoptotic proteins in the pathogenesis of OA, the genetic polymorphisms of two genes, one relat...
Autores principales: | Alimoradi, Nahid, Tahami, Mohammad, Firouzabadi, Negar, Haem, Elham, Ramezani, Amin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990216/ https://www.ncbi.nlm.nih.gov/pubmed/36879307 http://dx.doi.org/10.1186/s13075-023-03025-7 |
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