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p53 directly downregulates the expression of CDC20 to exert anti-tumor activity in mantle cell lymphoma

BACKGROUND: Cell cycle dysregulation characterized by cyclin D1 overexpression is common in mantle cell lymphoma (MCL), while mitotic disorder was less studied. Cell division cycle 20 homologue (CDC20), an essential mitotic regulator, was highly expressed in various tumors. Another common abnormalit...

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Detalles Bibliográficos
Autores principales: Chen, Yingtong, Yang, Ping, Wang, Jing, Gao, Shuang, Xiao, Shiyu, Zhang, Weilong, Zhu, Mingxia, Wang, Yanfang, Ke, Xiaoyan, Jing, Hongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990225/
https://www.ncbi.nlm.nih.gov/pubmed/36882855
http://dx.doi.org/10.1186/s40164-023-00381-7