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p53 directly downregulates the expression of CDC20 to exert anti-tumor activity in mantle cell lymphoma
BACKGROUND: Cell cycle dysregulation characterized by cyclin D1 overexpression is common in mantle cell lymphoma (MCL), while mitotic disorder was less studied. Cell division cycle 20 homologue (CDC20), an essential mitotic regulator, was highly expressed in various tumors. Another common abnormalit...
Autores principales: | Chen, Yingtong, Yang, Ping, Wang, Jing, Gao, Shuang, Xiao, Shiyu, Zhang, Weilong, Zhu, Mingxia, Wang, Yanfang, Ke, Xiaoyan, Jing, Hongmei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990225/ https://www.ncbi.nlm.nih.gov/pubmed/36882855 http://dx.doi.org/10.1186/s40164-023-00381-7 |
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