Recent advances in the plant epitranscriptome

Chemical modifications of RNAs, known as the epitranscriptome, are emerging as widespread regulatory mechanisms underlying gene regulation. The field of epitranscriptomics advances recently due to improved transcriptome-wide sequencing strategies for mapping RNA modifications and intensive character...

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Autores principales: Shen, Lisha, Ma, Jinqi, Li, Ping, Wu, Yujin, Yu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990323/
https://www.ncbi.nlm.nih.gov/pubmed/36882788
http://dx.doi.org/10.1186/s13059-023-02872-6
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author Shen, Lisha
Ma, Jinqi
Li, Ping
Wu, Yujin
Yu, Hao
author_facet Shen, Lisha
Ma, Jinqi
Li, Ping
Wu, Yujin
Yu, Hao
author_sort Shen, Lisha
collection PubMed
description Chemical modifications of RNAs, known as the epitranscriptome, are emerging as widespread regulatory mechanisms underlying gene regulation. The field of epitranscriptomics advances recently due to improved transcriptome-wide sequencing strategies for mapping RNA modifications and intensive characterization of writers, erasers, and readers that deposit, remove, and recognize RNA modifications, respectively. Herein, we review recent advances in characterizing plant epitranscriptome and its regulatory mechanisms in post-transcriptional gene regulation and diverse physiological processes, with main emphasis on N(6)-methyladenosine (m(6)A) and 5-methylcytosine (m(5)C). We also discuss the potential and challenges for utilization of epitranscriptome editing in crop improvement. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13059-023-02872-6.
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spelling pubmed-99903232023-03-08 Recent advances in the plant epitranscriptome Shen, Lisha Ma, Jinqi Li, Ping Wu, Yujin Yu, Hao Genome Biol Review Chemical modifications of RNAs, known as the epitranscriptome, are emerging as widespread regulatory mechanisms underlying gene regulation. The field of epitranscriptomics advances recently due to improved transcriptome-wide sequencing strategies for mapping RNA modifications and intensive characterization of writers, erasers, and readers that deposit, remove, and recognize RNA modifications, respectively. Herein, we review recent advances in characterizing plant epitranscriptome and its regulatory mechanisms in post-transcriptional gene regulation and diverse physiological processes, with main emphasis on N(6)-methyladenosine (m(6)A) and 5-methylcytosine (m(5)C). We also discuss the potential and challenges for utilization of epitranscriptome editing in crop improvement. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13059-023-02872-6. BioMed Central 2023-03-07 /pmc/articles/PMC9990323/ /pubmed/36882788 http://dx.doi.org/10.1186/s13059-023-02872-6 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Shen, Lisha
Ma, Jinqi
Li, Ping
Wu, Yujin
Yu, Hao
Recent advances in the plant epitranscriptome
title Recent advances in the plant epitranscriptome
title_full Recent advances in the plant epitranscriptome
title_fullStr Recent advances in the plant epitranscriptome
title_full_unstemmed Recent advances in the plant epitranscriptome
title_short Recent advances in the plant epitranscriptome
title_sort recent advances in the plant epitranscriptome
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990323/
https://www.ncbi.nlm.nih.gov/pubmed/36882788
http://dx.doi.org/10.1186/s13059-023-02872-6
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