Co-enrichment of CD8-positive T cells and macrophages is associated with clinical benefit of tislelizumab in solid tumors

BACKGROUND: Activated immune cells (IC) in the tumor microenvironment (TME) are critical for anti-tumor efficacy. Greater understanding of the dynamic diversity and crosstalk between IC is needed to clarify their association with immune checkpoint inhibitor efficacy. METHODS: Patients from three tis...

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Detalles Bibliográficos
Autores principales: Ye, Dingwei, Desai, Jayesh, Shi, Jingwen, Liu, Si-Yang Maggie, Shen, Wei, Liu, Tengfei, Shi, Yang, Wang, Dan, Liang, Liang, Yang, Silu, Ma, Xiaopeng, Jin, Wei, Zhang, Pei, Huang, Ruiqi, Shen, Zhirong, Zhang, Yun, Wu, Yi-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990338/
https://www.ncbi.nlm.nih.gov/pubmed/36879284
http://dx.doi.org/10.1186/s40364-023-00465-w

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