Cargando…
Remdesivir-induced conduction abnormalities: A molecular model-based explanation
Purpose: Remdesivir use in COVID-19 is associated with cardiac conduction abnormalities from unclear mechanisms. A proposed mechanism is the bioaccumulation of the intermediate metabolite GS-441524 resulting in exogenous activation of cardiac adenosine A1 due to the structural similarity between ade...
Autores principales: | Kingsley, Ryan, Rohlman, Christopher, Otto, Ashley, Chaudhary, Rahul, Phelan, David, Kirchoff, Robert |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990623/ https://www.ncbi.nlm.nih.gov/pubmed/36942295 http://dx.doi.org/10.3389/jpps.2023.11208 |
Ejemplares similares
-
COVID-19 Vaccination and Remdesivir are Associated With Protection From New or Increased Levels of Donor-Specific Antibodies Among Kidney Transplant Recipients Hospitalized With COVID-19
por: Killian, John T., et al.
Publicado: (2022) -
The mechanism of Leonuri Herba in improving polycystic ovary syndrome was analyzed based on network pharmacology and molecular docking
por: Wu, Mali, et al.
Publicado: (2023) -
Network pharmacology and molecular docking reveal the immunomodulatory mechanism of rhubarb peony decoction for the treatment of ulcerative colitis and irritable bowel syndrome
por: Zhai, Leilei, et al.
Publicado: (2023) -
Electrophysiological Abnormalities in Angelman Syndrome Correlate With Symptom Severity
por: Hipp, Joerg F., et al.
Publicado: (2021) -
Motor Abnormalities, Depression Risk, and Clinical Course in Adolescence
por: Damme, Katherine S.F., et al.
Publicado: (2021)