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Heterogeneity of tumor immune microenvironment of EGFR/ALK-positive tumors versus EGFR/ALK-negative tumors in resected brain metastases from lung adenocarcinoma

BACKGROUND: Previous studies found that lung adenocarcinomas (LUAD) with EGFR-positive and ALK-positive were less responsive to immunotherapy, which may be associated with a suppressive tumor immune microenvironment (TIME). Given the discordance in the TIME between primary lung cancer and brain meta...

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Detalles Bibliográficos
Autores principales:	Xiao, Gang, Li, Lifeng, Tanzhu, Guilong, Liu, Zhiyuan, Gao, Xuan, Wan, Xin, Xiao, Desheng, Chen, Liu, Xia, Xuefeng, Zhou, Rongrong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2023
Materias:	Immunotherapy Biomarkers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990629/ https://www.ncbi.nlm.nih.gov/pubmed/36868569 http://dx.doi.org/10.1136/jitc-2022-006243

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