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The role of CYP2C9*2, CYP2C9*3 and VKORC1-1639 variants on the susceptibility of upper gastrointestinal bleeding: A full case-control study
Purpose: To investigate whether interindividual variability in the CYP2C9 (*2 and *3 alleles) and VKORC1 (rs9923231) genes is associated with increased risk of upper gastrointestinal bleeding (UGIB) in users of non-steroidal anti-inflammatory drugs (NSAIDs) or low-dose aspirin (LDA). Methods: A full...
Autores principales: | Forgerini, Marcela, Urbano, Gustavo, De Nadai, Tales Rubens, Batah, Sabrina Setembre, Fabro, Alexandre Todorovic, De Carvalho Mastroianni, Patrícia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990631/ https://www.ncbi.nlm.nih.gov/pubmed/36942299 http://dx.doi.org/10.3389/jpps.2023.11136 |
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