Ambra1 modulates the tumor immune microenvironment and response to PD-1 blockade in melanoma

BACKGROUND: Loss of Ambra1 (autophagy and beclin 1 regulator 1), a multifunctional scaffold protein, promotes the formation of nevi and contributes to several phases of melanoma development. The suppressive functions of Ambra1 in melanoma are mediated by negative regulation of cell proliferation and...

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Detalles Bibliográficos
Autores principales: Frias, Alex, Di Leo, Luca, Antoranz, Asier, Nazerai, Loulieta, Carretta, Marco, Bodemeyer, Valérie, Pagliuca, Chiara, Dahl, Christina, Claps, Giuseppina, Mandelli, Giulio Eugenio, Andhari, Madhavi Dipak, Pacheco, Maria Pires, Sauter, Thomas, Robert, Caroline, Guldberg, Per, Madsen, Daniel Hargbøl, Cecconi, Francesco, Bosisio, Francesca Maria, De Zio, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990656/
https://www.ncbi.nlm.nih.gov/pubmed/36868570
http://dx.doi.org/10.1136/jitc-2022-006389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990656/
https://www.ncbi.nlm.nih.gov/pubmed/36868570
http://dx.doi.org/10.1136/jitc-2022-006389

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