Asymmetric ring-opening reactions of donor–acceptor cyclopropanes with 1,3-cyclodiones

Asymmetric ring-opening reactions of donor–acceptor cyclopropanes with 1,3-cyclodiones have been established for the synthesis of enantioenriched γ-hydroxybutyric acid derivatives in the presence of Cu(ii)/trisoxazoline catalyst. These reactions offered the desired products in 70% to 93% yields with...

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Detalles Bibliográficos
Autores principales: Zhang, Dongxin, Chen, Lvjia, Deng, Huiqing, Zhang, Ying, Cheng, Qihang, Zhang, Qian-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990749/
https://www.ncbi.nlm.nih.gov/pubmed/36895764
http://dx.doi.org/10.1039/d2ra08257h
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author Zhang, Dongxin
Chen, Lvjia
Deng, Huiqing
Zhang, Ying
Cheng, Qihang
Zhang, Qian-Feng
author_facet Zhang, Dongxin
Chen, Lvjia
Deng, Huiqing
Zhang, Ying
Cheng, Qihang
Zhang, Qian-Feng
author_sort Zhang, Dongxin
collection PubMed
description Asymmetric ring-opening reactions of donor–acceptor cyclopropanes with 1,3-cyclodiones have been established for the synthesis of enantioenriched γ-hydroxybutyric acid derivatives in the presence of Cu(ii)/trisoxazoline catalyst. These reactions offered the desired products in 70% to 93% yields with 79% to 99% enantiomeric excesses.
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spelling pubmed-99907492023-03-08 Asymmetric ring-opening reactions of donor–acceptor cyclopropanes with 1,3-cyclodiones Zhang, Dongxin Chen, Lvjia Deng, Huiqing Zhang, Ying Cheng, Qihang Zhang, Qian-Feng RSC Adv Chemistry Asymmetric ring-opening reactions of donor–acceptor cyclopropanes with 1,3-cyclodiones have been established for the synthesis of enantioenriched γ-hydroxybutyric acid derivatives in the presence of Cu(ii)/trisoxazoline catalyst. These reactions offered the desired products in 70% to 93% yields with 79% to 99% enantiomeric excesses. The Royal Society of Chemistry 2023-03-07 /pmc/articles/PMC9990749/ /pubmed/36895764 http://dx.doi.org/10.1039/d2ra08257h Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Zhang, Dongxin
Chen, Lvjia
Deng, Huiqing
Zhang, Ying
Cheng, Qihang
Zhang, Qian-Feng
Asymmetric ring-opening reactions of donor–acceptor cyclopropanes with 1,3-cyclodiones
title Asymmetric ring-opening reactions of donor–acceptor cyclopropanes with 1,3-cyclodiones
title_full Asymmetric ring-opening reactions of donor–acceptor cyclopropanes with 1,3-cyclodiones
title_fullStr Asymmetric ring-opening reactions of donor–acceptor cyclopropanes with 1,3-cyclodiones
title_full_unstemmed Asymmetric ring-opening reactions of donor–acceptor cyclopropanes with 1,3-cyclodiones
title_short Asymmetric ring-opening reactions of donor–acceptor cyclopropanes with 1,3-cyclodiones
title_sort asymmetric ring-opening reactions of donor–acceptor cyclopropanes with 1,3-cyclodiones
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990749/
https://www.ncbi.nlm.nih.gov/pubmed/36895764
http://dx.doi.org/10.1039/d2ra08257h
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AT denghuiqing asymmetricringopeningreactionsofdonoracceptorcyclopropaneswith13cyclodiones
AT zhangying asymmetricringopeningreactionsofdonoracceptorcyclopropaneswith13cyclodiones
AT chengqihang asymmetricringopeningreactionsofdonoracceptorcyclopropaneswith13cyclodiones
AT zhangqianfeng asymmetricringopeningreactionsofdonoracceptorcyclopropaneswith13cyclodiones

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