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Pallidal deep brain stimulation in a patient with nonketotic hyperglycemic hemichorea

BACKGROUND: Hyperkinetic movement disorders secondary to brain tissue damage due to hyperglycemia are a rare complication of diabetes mellitus. Nonketotic hyperglycemic hemichorea (NH-HC) is characterized by a rapid onset of involuntary movements after increased serum glucose levels. CASE DESCRIPTIO...

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Autores principales: Jergas, Hannah, Baldermann, Juan C., Wirths, Jochen, Barbe, Michael T., Visser-Vandewalle, Veerle, Andrade, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientific Scholar 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990764/
https://www.ncbi.nlm.nih.gov/pubmed/36895223
http://dx.doi.org/10.25259/SNI_716_2022
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author Jergas, Hannah
Baldermann, Juan C.
Wirths, Jochen
Barbe, Michael T.
Visser-Vandewalle, Veerle
Andrade, Pablo
author_facet Jergas, Hannah
Baldermann, Juan C.
Wirths, Jochen
Barbe, Michael T.
Visser-Vandewalle, Veerle
Andrade, Pablo
author_sort Jergas, Hannah
collection PubMed
description BACKGROUND: Hyperkinetic movement disorders secondary to brain tissue damage due to hyperglycemia are a rare complication of diabetes mellitus. Nonketotic hyperglycemic hemichorea (NH-HC) is characterized by a rapid onset of involuntary movements after increased serum glucose levels. CASE DESCRIPTION: We report on a case of a 62-year-old male patient with a 28-year history of Type II diabetes mellitus with NH-HC following an infect-associated exacerbation of blood glucose levels. Choreiform movements of the right upper extremity, face, and trunk persisted 6 months after onset. Due to failure of conservative treatments, we opted for unilateral deep brain stimulation of the globus pallidus internus, which led to complete cessation of symptoms within a week after initial programming. Symptom control was still satisfactory 12 months after surgery. No side-effects or surgery-associated complications were observed. CONCLUSION: Globus pallidus internus DBS is an effective and safe treatment option for hyperkinetic movement disorders secondary to brain tissue damage caused by hyperglycemia. Postoperatively, stimulation effects can be observed quickly and effects persist even after 12 months.
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spelling pubmed-99907642023-03-08 Pallidal deep brain stimulation in a patient with nonketotic hyperglycemic hemichorea Jergas, Hannah Baldermann, Juan C. Wirths, Jochen Barbe, Michael T. Visser-Vandewalle, Veerle Andrade, Pablo Surg Neurol Int Case Report BACKGROUND: Hyperkinetic movement disorders secondary to brain tissue damage due to hyperglycemia are a rare complication of diabetes mellitus. Nonketotic hyperglycemic hemichorea (NH-HC) is characterized by a rapid onset of involuntary movements after increased serum glucose levels. CASE DESCRIPTION: We report on a case of a 62-year-old male patient with a 28-year history of Type II diabetes mellitus with NH-HC following an infect-associated exacerbation of blood glucose levels. Choreiform movements of the right upper extremity, face, and trunk persisted 6 months after onset. Due to failure of conservative treatments, we opted for unilateral deep brain stimulation of the globus pallidus internus, which led to complete cessation of symptoms within a week after initial programming. Symptom control was still satisfactory 12 months after surgery. No side-effects or surgery-associated complications were observed. CONCLUSION: Globus pallidus internus DBS is an effective and safe treatment option for hyperkinetic movement disorders secondary to brain tissue damage caused by hyperglycemia. Postoperatively, stimulation effects can be observed quickly and effects persist even after 12 months. Scientific Scholar 2023-01-27 /pmc/articles/PMC9990764/ /pubmed/36895223 http://dx.doi.org/10.25259/SNI_716_2022 Text en Copyright: © 2023 Surgical Neurology International https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, transform, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Jergas, Hannah
Baldermann, Juan C.
Wirths, Jochen
Barbe, Michael T.
Visser-Vandewalle, Veerle
Andrade, Pablo
Pallidal deep brain stimulation in a patient with nonketotic hyperglycemic hemichorea
title Pallidal deep brain stimulation in a patient with nonketotic hyperglycemic hemichorea
title_full Pallidal deep brain stimulation in a patient with nonketotic hyperglycemic hemichorea
title_fullStr Pallidal deep brain stimulation in a patient with nonketotic hyperglycemic hemichorea
title_full_unstemmed Pallidal deep brain stimulation in a patient with nonketotic hyperglycemic hemichorea
title_short Pallidal deep brain stimulation in a patient with nonketotic hyperglycemic hemichorea
title_sort pallidal deep brain stimulation in a patient with nonketotic hyperglycemic hemichorea
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990764/
https://www.ncbi.nlm.nih.gov/pubmed/36895223
http://dx.doi.org/10.25259/SNI_716_2022
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