Cargando…
Myeloid sarcoma of the thoracic spine: A case report
BACKGROUND: Myeloid sarcoma is an uncommon malignant neoplasm that typically arises at extramedullary sites and is associated with a diagnosis of acute myeloid leukemia. While myeloid sarcoma can involve any organ, central nervous system involvement is rare, particularly in the adult population. CAS...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Scientific Scholar
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990772/ https://www.ncbi.nlm.nih.gov/pubmed/36895207 http://dx.doi.org/10.25259/SNI_1167_2022 |
_version_ | 1784902005926395904 |
---|---|
author | Patel, Tarika Deepak Uzoaru, Ikechukwu Sutton, Bradley P. Arnold, Paul M. |
author_facet | Patel, Tarika Deepak Uzoaru, Ikechukwu Sutton, Bradley P. Arnold, Paul M. |
author_sort | Patel, Tarika Deepak |
collection | PubMed |
description | BACKGROUND: Myeloid sarcoma is an uncommon malignant neoplasm that typically arises at extramedullary sites and is associated with a diagnosis of acute myeloid leukemia. While myeloid sarcoma can involve any organ, central nervous system involvement is rare, particularly in the adult population. CASE DESCRIPTION: An 87-year-old female presented with progressive paraparesis of 5 days’ duration. The magnetic resonance imaging (MRI) revealed an epidural tumor from T4 to T7 with cord compression. When she underwent a laminectomy for tumor resection, the pathology revealed a myeloid sarcoma with monocytic differentiation. Although she improved postoperatively, she elected to pursue hospice care and expired 4 months later. CONCLUSION: Myeloid sarcoma is an uncommon malignant spinal neoplasm rarely seen in adults. For this 87-year-old female, MRI-documented cord compression warranted decompressive surgery. Although this patient did not opt for adjuvant therapy, other patients with such lesions may undergo additional chemotherapy or radiation therapy. Nevertheless, optimal management for such malignant tumor is still undefined. |
format | Online Article Text |
id | pubmed-9990772 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Scientific Scholar |
record_format | MEDLINE/PubMed |
spelling | pubmed-99907722023-03-08 Myeloid sarcoma of the thoracic spine: A case report Patel, Tarika Deepak Uzoaru, Ikechukwu Sutton, Bradley P. Arnold, Paul M. Surg Neurol Int Case Report BACKGROUND: Myeloid sarcoma is an uncommon malignant neoplasm that typically arises at extramedullary sites and is associated with a diagnosis of acute myeloid leukemia. While myeloid sarcoma can involve any organ, central nervous system involvement is rare, particularly in the adult population. CASE DESCRIPTION: An 87-year-old female presented with progressive paraparesis of 5 days’ duration. The magnetic resonance imaging (MRI) revealed an epidural tumor from T4 to T7 with cord compression. When she underwent a laminectomy for tumor resection, the pathology revealed a myeloid sarcoma with monocytic differentiation. Although she improved postoperatively, she elected to pursue hospice care and expired 4 months later. CONCLUSION: Myeloid sarcoma is an uncommon malignant spinal neoplasm rarely seen in adults. For this 87-year-old female, MRI-documented cord compression warranted decompressive surgery. Although this patient did not opt for adjuvant therapy, other patients with such lesions may undergo additional chemotherapy or radiation therapy. Nevertheless, optimal management for such malignant tumor is still undefined. Scientific Scholar 2023-01-27 /pmc/articles/PMC9990772/ /pubmed/36895207 http://dx.doi.org/10.25259/SNI_1167_2022 Text en Copyright: © 2023 Surgical Neurology International https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, transform, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Patel, Tarika Deepak Uzoaru, Ikechukwu Sutton, Bradley P. Arnold, Paul M. Myeloid sarcoma of the thoracic spine: A case report |
title | Myeloid sarcoma of the thoracic spine: A case report |
title_full | Myeloid sarcoma of the thoracic spine: A case report |
title_fullStr | Myeloid sarcoma of the thoracic spine: A case report |
title_full_unstemmed | Myeloid sarcoma of the thoracic spine: A case report |
title_short | Myeloid sarcoma of the thoracic spine: A case report |
title_sort | myeloid sarcoma of the thoracic spine: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990772/ https://www.ncbi.nlm.nih.gov/pubmed/36895207 http://dx.doi.org/10.25259/SNI_1167_2022 |
work_keys_str_mv | AT pateltarikadeepak myeloidsarcomaofthethoracicspineacasereport AT uzoaruikechukwu myeloidsarcomaofthethoracicspineacasereport AT suttonbradleyp myeloidsarcomaofthethoracicspineacasereport AT arnoldpaulm myeloidsarcomaofthethoracicspineacasereport |