Loss of the m6A methyltransferase METTL3 in monocyte-derived macrophages ameliorates Alzheimer’s disease pathology in mice

Alzheimer’s disease (AD) is a heterogeneous disease with complex clinicopathological characteristics. To date, the role of m6A RNA methylation in monocyte-derived macrophages involved in the progression of AD is unknown. In our study, we found that methyltransferase-like 3 (METTL3) deficiency in mon...

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Detalles Bibliográficos
Autores principales: Yin, Huilong, Ju, Zhuan, Zheng, Minhua, Zhang, Xiang, Zuo, Wenjie, Wang, Yidi, Ding, Xiaochen, Zhang, Xiaofang, Peng, Yingran, Li, Jiadi, Yang, Angang, Zhang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990945/
https://www.ncbi.nlm.nih.gov/pubmed/36881554
http://dx.doi.org/10.1371/journal.pbio.3002017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990945/
https://www.ncbi.nlm.nih.gov/pubmed/36881554
http://dx.doi.org/10.1371/journal.pbio.3002017

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