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Local delivery of FK506 to a nerve allograft is comparable to systemic delivery at suppressing allogeneic graft rejection
The objective of this study was to determine if locally delivered FK506 could prevent allogeneic nerve graft rejection long enough to allow axon regeneration to pass through the nerve graft. An 8mm mouse sciatic nerve gap injury repaired with a nerve allograft was used to assess the effectiveness of...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990949/ https://www.ncbi.nlm.nih.gov/pubmed/36881592 http://dx.doi.org/10.1371/journal.pone.0281911 |