A3 CROHN’S DISEASE PROTEOLYTIC MICROBIOTA ENHANCES INFLAMMATION THROUGH PAR2 PATHWAY IN GNOTOBIOTIC MICE

BACKGROUND: An imbalance in host proteases has been implicated in inflammatory bowel disease (IBD). Recent evidence implicates microbial proteolytic activity (PA) in ulcerative colitis but whether it also plays a role in Crohn’s disease (CD) remains unclear. PURPOSE: We therefore investigated the co...

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Detalles Bibliográficos
Autores principales: Hann, A, Santiago Badenas, A, Galipeau, H J, Constante, M, Libertucci, J, Rahmani, S, Jackson, K, Rueda, G, Rossi, L, Ramachandran, R, Ruf, W, Caminero, A, Bercik, P, Verdu, E F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Oral Presentations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9991128/
http://dx.doi.org/10.1093/jcag/gwac036.003

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