A39 HEALTHY FIRST-DEGREE RELATIVES FROM MULTIPLEX FAMILIES VERSUS SIMPLEX HARBOR A HIGHER RISK OF DEVELOPING CROHN'S DISEASE AND ARE ASSOCIATED WITH SUBCLINICAL INFLAMMATION AND ALTERED MICROBIOME COMPOSITION

BACKGROUND: Healthy individuals within families with multiple affected members (multiplex families) with Crohn’s disease (CD) have a notably high risk of developing CD. No large prospective pre-disease cohort has assessed differences in preclinical intestinal inflammation, permeability, fecal microb...

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Detalles Bibliográficos
Autores principales: Olivera, P, Martinez-Lozano, H, Leibovitzh, H, Xue, M, Xu, W, Espin-Garcia, O, Madsen, K, Meddings, J, Guttman, D, Griffiths, A, Huynh, H, Turner, D, Panancionne, R, Steinhart, H, Aumais, G, Jacobson, K, Mack, D, Marshall, J, Moayyedi, P, Lee, S -H, Turpin, W, Croitoru, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Poster of Distinction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9991131/
http://dx.doi.org/10.1093/jcag/gwac036.039

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