A277 A NOVEL PH-SENSITIVE Μ-OPIOID RECEPTOR AGONIST THAT DOES NOT INDUCE TOLERANCE IN A COLITIS MOUSE MODEL

BACKGROUND: Adequate pain control in inflammatory bowel disease (IBD) can require opioids due to their high analgesic potency. The long-term use of opioids, however, is limited by the development of tolerance. This leads to reduced analgesic efficacy over time, resulting in escalating opioid dosing...

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Detalles Bibliográficos
Autores principales: Degro, C E, Jiménez-Vargas, N N, Schincariol, H M, Tsang, Q K, Guzman-Rodriguez, M, Lomax, A E, Reed, D E, Stein, C, Bunnett, N W, Vanner, S J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Poster Presentations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9991237/
http://dx.doi.org/10.1093/jcag/gwac036.277

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