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A70 FECAL-ADHERENT MUCUS IS A NON-INVASIVE SOURCE OF PRIMARY HUMAN MUC2 FOR STRUCTURAL AND FUNCTIONAL CHARACTERIZATION IN HEALTH AND DISEASE

BACKGROUND: The gel-forming O-glycoprotein Mucin-2 (MUC2) is a key mediator of host-microbe homeostasis in part by forming a barrier to segregate inflammatory microbes from distal colon tissues. While animal models have provided insights into how Muc2 functions, relatively few studies have explored...

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Detalles Bibliográficos
Autores principales: Fancy, N, Melvin, M, N, N, Kazemian, N, D’Aloisio, L, Davidson-Hunt, S, Chadee, K, Pakpour, S, Ghosh, S, Gibson, D, Zandberg, W, Bergstrom, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9991287/
http://dx.doi.org/10.1093/jcag/gwac036.070

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