Cargando…
A165 FCGBP IN THE COLON IS SPATIALLY DEPENDENT ON MUC2 EXPRESSION AND IS DEGRADED IN DEXTRAN SULFATE SODIUM-INDUCED COLITIS
BACKGROUND: The colonic mucus bilayer is an integral innate host defense mechanism that provides a physical barrier separating the lumen and its contents from the underlying epithelium. This essential barrier is produced by specialized secretory goblet cells of which Muc2 mucin is its primary produc...
Autores principales: | Kim, A, Moreau, F, Chadee, K |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9991292/ http://dx.doi.org/10.1093/jcag/gwac036.165 |
Ejemplares similares
-
A198 COLONIC MUC2 MUCIN IS STABILIZED BY FCGBP TO RESIST SALMONELLA TYPHIMURIUM INVASION IN GOBLET CELLS
por: Gorman, H, et al.
Publicado: (2022) -
A230 A MISSENSE MUTATION IN GOBLET CELL PROTEIN FCGBP ALTERS THE GLYCOMIC PROFILE AND FUNCTION OF THE COLONIC MUCUS BARRIER
por: Gorman, H, et al.
Publicado: (2023) -
Tumor Necrosis Factor-α and Muc2 Mucin Play Major Roles in Disease Onset and Progression in Dextran Sodium Sulphate-Induced Colitis
por: Dharmani, Poonam, et al.
Publicado: (2011) -
Histological and ultrastructural changes of the colon in dextran sodium sulfate-induced mouse colitis
por: Xu, Xiaojuan, et al.
Publicado: (2020) -
Colonic Epithelial Circadian Disruption Worsens Dextran Sulfate Sodium–Induced Colitis
por: Jochum, Sarah B, et al.
Publicado: (2022)