A174 A NOVEL MECHANISM OF CROHN’S DISEASE SEVERITY IN WOMEN: EVALUATING THE IMPACT OF AN ESTROGEN-FARNESOID X RECEPTOR INTERACTION ON INTESTINAL BARRIER FUNCTION

BACKGROUND: Crohn’s disease (CD) is associated with deficits in intestinal barrier function. Activation of bile acid-sensing nuclear receptor Farnesoid X receptor (NR1H4, FXR) is associated with protective effects against reduced intestinal barrier function; namely through promoting tight junction c...

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Detalles Bibliográficos
Autores principales: Taylor, D, Donovan, L, Choi, J, Kim, R, Schwarz, U, Wilson, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Poster Presentations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9991304/
http://dx.doi.org/10.1093/jcag/gwac036.174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9991304/
http://dx.doi.org/10.1093/jcag/gwac036.174

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