Use of Continuous Intravenous Anakinra Infusion in Multisystem Inflammatory Syndrome in Children

Coronavirus disease (COVID-19) is an emergency pandemic with a high mortality rate worldwide. One of its complications in children is developing multisystemic inflammatory syndrome related to cytokine storm. Anakinra is a recombinant human interleukin-1 (IL-1) receptor antagonist used to suppress th...

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Detalles Bibliográficos
Autores principales: Alolayan, Abdulaziz, Aldamegh, Abdullah S., Alkhayrat, Azzah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9991479/
https://www.ncbi.nlm.nih.gov/pubmed/36895203
http://dx.doi.org/10.1155/2023/8530060
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author Alolayan, Abdulaziz
Aldamegh, Abdullah S.
Alkhayrat, Azzah
author_facet Alolayan, Abdulaziz
Aldamegh, Abdullah S.
Alkhayrat, Azzah
author_sort Alolayan, Abdulaziz
collection PubMed
description Coronavirus disease (COVID-19) is an emergency pandemic with a high mortality rate worldwide. One of its complications in children is developing multisystemic inflammatory syndrome related to cytokine storm. Anakinra is a recombinant human interleukin-1 (IL-1) receptor antagonist used to suppress the exaggerated inflammatory response in such conditions, and it is potentially lifesaving in a cytokine storm. We present the case of a patient with critical COVID-19 associated with multisystem inflammatory syndrome in children (MIS-C) successfully treated with anakinra intravenous (IV) infusion.
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spelling pubmed-99914792023-03-08 Use of Continuous Intravenous Anakinra Infusion in Multisystem Inflammatory Syndrome in Children Alolayan, Abdulaziz Aldamegh, Abdullah S. Alkhayrat, Azzah Case Rep Crit Care Case Report Coronavirus disease (COVID-19) is an emergency pandemic with a high mortality rate worldwide. One of its complications in children is developing multisystemic inflammatory syndrome related to cytokine storm. Anakinra is a recombinant human interleukin-1 (IL-1) receptor antagonist used to suppress the exaggerated inflammatory response in such conditions, and it is potentially lifesaving in a cytokine storm. We present the case of a patient with critical COVID-19 associated with multisystem inflammatory syndrome in children (MIS-C) successfully treated with anakinra intravenous (IV) infusion. Hindawi 2023-02-28 /pmc/articles/PMC9991479/ /pubmed/36895203 http://dx.doi.org/10.1155/2023/8530060 Text en Copyright © 2023 Abdulaziz Alolayan et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Alolayan, Abdulaziz
Aldamegh, Abdullah S.
Alkhayrat, Azzah
Use of Continuous Intravenous Anakinra Infusion in Multisystem Inflammatory Syndrome in Children
title Use of Continuous Intravenous Anakinra Infusion in Multisystem Inflammatory Syndrome in Children
title_full Use of Continuous Intravenous Anakinra Infusion in Multisystem Inflammatory Syndrome in Children
title_fullStr Use of Continuous Intravenous Anakinra Infusion in Multisystem Inflammatory Syndrome in Children
title_full_unstemmed Use of Continuous Intravenous Anakinra Infusion in Multisystem Inflammatory Syndrome in Children
title_short Use of Continuous Intravenous Anakinra Infusion in Multisystem Inflammatory Syndrome in Children
title_sort use of continuous intravenous anakinra infusion in multisystem inflammatory syndrome in children
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9991479/
https://www.ncbi.nlm.nih.gov/pubmed/36895203
http://dx.doi.org/10.1155/2023/8530060
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AT alkhayratazzah useofcontinuousintravenousanakinrainfusioninmultisysteminflammatorysyndromeinchildren

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