Clostridioides difficile Binary Toxin Binding Component Increases Virulence in a Hamster Model

BACKGROUND: Clostridioides difficile is the leading cause of hospital-acquired gastrointestinal infection, in part due to the existence of binary toxin (CDT)-expressing hypervirulent strains. Although the effects of the CDT holotoxin on disease pathogenesis have been previously studied, we sought to...

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Detalles Bibliográficos
Autores principales: Simpson, Morgan, Bilverstone, Terry, Leslie, Jhansi, Donlan, Alexandra, Uddin, Md Jashim, Petri, William A, Marin, Natasha, Kuehne, Sarah, Minton, Nigel P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Major Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9991586/
https://www.ncbi.nlm.nih.gov/pubmed/36895287
http://dx.doi.org/10.1093/ofid/ofad040

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