Disruption to the FOXO-PRDM1 axis resulting from deletions of chromosome 6 in acute lymphoblastic leukaemia

A common problem in the study of human malignancy is the elucidation of cancer driver mechanisms associated with recurrent deletion of regions containing multiple genes. Taking B-cell acute lymphoblastic leukaemia (B-ALL) and large deletions of 6q [del(6q)] as a model, we integrated analysis of func...

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Detalles Bibliográficos
Autores principales: Sinclair, Paul B., Cranston, Ruth E., Raninga, Prahlad, Cheng, Joanna, Hanna, Rebecca, Hawking, Zoe, Hair, Steven, Ryan, Sarra L., Enshaei, Amir, Nakjang, Sirintra, Rand, Vikki, Blair, Helen J., Moorman, Anthony V., Heidenreich, Olaf, Harrison, Christine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9991907/
https://www.ncbi.nlm.nih.gov/pubmed/36670235
http://dx.doi.org/10.1038/s41375-023-01816-0

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