IMM0306, a fusion protein of CD20 mAb with the CD47 binding domain of SIRPα, exerts excellent cancer killing efficacy by activating both macrophages and NK cells via blockade of CD47-SIRPα interaction and FcɣR engagement by simultaneously binding to CD47 and CD20 of B cells

Detalles Bibliográficos
Autores principales: Yu, Jifeng, Li, Song, Chen, Dianze, Liu, Dandan, Guo, Huiqin, Yang, Chunmei, Zhang, Wei, Zhang, Li, Zhao, Gui, Tu, Xiaoping, Peng, Liang, Liu, Sijin, Bai, Xing, Song, Yongping, Jiang, Zhongxing, Zhang, Ruliang, Tian, Wenzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9991911/
https://www.ncbi.nlm.nih.gov/pubmed/36575242
http://dx.doi.org/10.1038/s41375-022-01805-9

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