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Immunophenotypic aberrant hematopoietic stem cells in myelodysplastic syndromes: a biomarker for leukemic progression

Myelodysplastic syndromes (MDS) comprise hematological disorders that originate from the neoplastic transformation of hematopoietic stem cells (HSCs). However, discrimination between HSCs and their neoplastic counterparts in MDS-derived bone marrows (MDS-BMs) remains challenging. We hypothesized tha...

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Detalles Bibliográficos
Autores principales: van Spronsen, Margot F., Hanekamp, Diana, Westers, Theresia M., van Gils, Noortje, Vermue, Eline, Rutten, Arjo, Jansen, Joop H., Lissenberg-Witte, Birgit I., Smit, Linda, Schuurhuis, Gerrit J., van de Loosdrecht, Arjan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9991914/
https://www.ncbi.nlm.nih.gov/pubmed/36792658
http://dx.doi.org/10.1038/s41375-023-01811-5

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