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Isocitrate-dehydrogenase-mutant lower grade glioma in elderly patients: treatment and outcome in a molecularly characterized contemporary cohort

PURPOSE: Lower-grade glioma (LGG) is rare among patients above the age of 60 (“elderly”). Previous studies reported poor outcome, likely due to the inclusion of isocitrate dehydrogenase (IDH) wildtype astrocytomas and advocated defensive surgical and adjuvant treatment. This study set out to questio...

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Detalles Bibliográficos
Autores principales: Dao Trong, P., Gluszak, M., Reuss, D., von Deimling, A., Wick, A., König, L., Debus, J., Herold-Mende, C., Unterberg, A., Jungk, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992027/
https://www.ncbi.nlm.nih.gov/pubmed/36648586
http://dx.doi.org/10.1007/s11060-022-04230-1