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Heinz body hemolysis following extended use phenazopyridine in a post‐HCT patient with hemorrhagic cystitis: An old problem for a new generation

Hemorrhagic cystitis is a common complication following the use of cyclophosphamide. Associated dysuria can be painful and there are few good options to relieve pain. Phenazopyridine has historically been utilized for dysuria and is available over the counter. However, it is associated with hematolo...

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Autores principales: Ferdjallah, Asmaa, Long, Susie, Dayton, Vanessa, Gupta, Ashish O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992140/
https://www.ncbi.nlm.nih.gov/pubmed/36911643
http://dx.doi.org/10.1002/ccr3.7012
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author Ferdjallah, Asmaa
Long, Susie
Dayton, Vanessa
Gupta, Ashish O.
author_facet Ferdjallah, Asmaa
Long, Susie
Dayton, Vanessa
Gupta, Ashish O.
author_sort Ferdjallah, Asmaa
collection PubMed
description Hemorrhagic cystitis is a common complication following the use of cyclophosphamide. Associated dysuria can be painful and there are few good options to relieve pain. Phenazopyridine has historically been utilized for dysuria and is available over the counter. However, it is associated with hematologic side effects with prolonged use. Here we present a case of a patient who developed Heinz body hemolysis following prolonged administration of phenazopyridine to treat cyclophosphamide‐induced hemorrhagic cystitis following hematopoietic stem cell transplant.
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spelling pubmed-99921402023-03-09 Heinz body hemolysis following extended use phenazopyridine in a post‐HCT patient with hemorrhagic cystitis: An old problem for a new generation Ferdjallah, Asmaa Long, Susie Dayton, Vanessa Gupta, Ashish O. Clin Case Rep Case Report Hemorrhagic cystitis is a common complication following the use of cyclophosphamide. Associated dysuria can be painful and there are few good options to relieve pain. Phenazopyridine has historically been utilized for dysuria and is available over the counter. However, it is associated with hematologic side effects with prolonged use. Here we present a case of a patient who developed Heinz body hemolysis following prolonged administration of phenazopyridine to treat cyclophosphamide‐induced hemorrhagic cystitis following hematopoietic stem cell transplant. John Wiley and Sons Inc. 2023-03-07 /pmc/articles/PMC9992140/ /pubmed/36911643 http://dx.doi.org/10.1002/ccr3.7012 Text en © 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ferdjallah, Asmaa
Long, Susie
Dayton, Vanessa
Gupta, Ashish O.
Heinz body hemolysis following extended use phenazopyridine in a post‐HCT patient with hemorrhagic cystitis: An old problem for a new generation
title Heinz body hemolysis following extended use phenazopyridine in a post‐HCT patient with hemorrhagic cystitis: An old problem for a new generation
title_full Heinz body hemolysis following extended use phenazopyridine in a post‐HCT patient with hemorrhagic cystitis: An old problem for a new generation
title_fullStr Heinz body hemolysis following extended use phenazopyridine in a post‐HCT patient with hemorrhagic cystitis: An old problem for a new generation
title_full_unstemmed Heinz body hemolysis following extended use phenazopyridine in a post‐HCT patient with hemorrhagic cystitis: An old problem for a new generation
title_short Heinz body hemolysis following extended use phenazopyridine in a post‐HCT patient with hemorrhagic cystitis: An old problem for a new generation
title_sort heinz body hemolysis following extended use phenazopyridine in a post‐hct patient with hemorrhagic cystitis: an old problem for a new generation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992140/
https://www.ncbi.nlm.nih.gov/pubmed/36911643
http://dx.doi.org/10.1002/ccr3.7012
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