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Whole genome methylation combined with RNA-seq reveals the protective effects of Gualou-Xiebai herb pair in foam cells through DNA methylation mediated PI3K-AKT signaling pathway
DNA methylation, including aberrant hypomethylation and hypermethylation, plays a significant role in atherosclerosis (AS); therefore, targeting the unbalanced methylation in AS is a potential treatment strategy. Gualou-xiebai herb pair (GXHP), a classic herb combination, have been used for the trea...
Autores principales: | Jia, Zijun, Mei, Jun, Zhang, Yan, Wang, Ya, Wang, Hongqin, Wang, Anlu, Xu, Fengqin, Zhou, Qingbing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992180/ https://www.ncbi.nlm.nih.gov/pubmed/36911738 http://dx.doi.org/10.3389/fimmu.2023.1054014 |
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