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The cerebellum and anxiety

Although the cerebellum is traditionally known for its role in motor functions, recent evidence points toward the additional involvement of the cerebellum in an array of non-motor functions. One such non-motor function is anxiety behavior: a series of recent studies now implicate the cerebellum in a...

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Detalles Bibliográficos
Autores principales: Chin, Pei Wern, Augustine, George J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992220/
https://www.ncbi.nlm.nih.gov/pubmed/36909285
http://dx.doi.org/10.3389/fncel.2023.1130505
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author Chin, Pei Wern
Augustine, George J.
author_facet Chin, Pei Wern
Augustine, George J.
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description Although the cerebellum is traditionally known for its role in motor functions, recent evidence points toward the additional involvement of the cerebellum in an array of non-motor functions. One such non-motor function is anxiety behavior: a series of recent studies now implicate the cerebellum in anxiety. Here, we review evidence regarding the possible role of the cerebellum in anxiety—ranging from clinical studies to experimental manipulation of neural activity—that collectively points toward a role for the cerebellum, and possibly a specific topographical locus within the cerebellum, as one of the orchestrators of anxiety responses.
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spelling pubmed-99922202023-03-09 The cerebellum and anxiety Chin, Pei Wern Augustine, George J. Front Cell Neurosci Cellular Neuroscience Although the cerebellum is traditionally known for its role in motor functions, recent evidence points toward the additional involvement of the cerebellum in an array of non-motor functions. One such non-motor function is anxiety behavior: a series of recent studies now implicate the cerebellum in anxiety. Here, we review evidence regarding the possible role of the cerebellum in anxiety—ranging from clinical studies to experimental manipulation of neural activity—that collectively points toward a role for the cerebellum, and possibly a specific topographical locus within the cerebellum, as one of the orchestrators of anxiety responses. Frontiers Media S.A. 2023-02-22 /pmc/articles/PMC9992220/ /pubmed/36909285 http://dx.doi.org/10.3389/fncel.2023.1130505 Text en Copyright © 2023 Chin and Augustine. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cellular Neuroscience
Chin, Pei Wern
Augustine, George J.
The cerebellum and anxiety
title The cerebellum and anxiety
title_full The cerebellum and anxiety
title_fullStr The cerebellum and anxiety
title_full_unstemmed The cerebellum and anxiety
title_short The cerebellum and anxiety
title_sort cerebellum and anxiety
topic Cellular Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992220/
https://www.ncbi.nlm.nih.gov/pubmed/36909285
http://dx.doi.org/10.3389/fncel.2023.1130505
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