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Molar-incisor hypomineralisation prevalence in a cohort of Australian children with type 1 diabetes

PURPOSE: Systemic diseases or drugs administered early in life may cause a disruption in amelogenesis and contribute to the qualitative defect of enamel described as molar–incisor hypomineralisation (MIH). Therefore, an increase in prevalence of MIH in children with type 1 diabetes (T1D) may be expe...

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Autores principales: Lim, C., Jensen, E. D., Poirier, B. F., Sethi, S., Smart, G., Peña, A. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992226/
https://www.ncbi.nlm.nih.gov/pubmed/36348176
http://dx.doi.org/10.1007/s40368-022-00765-z
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author Lim, C.
Jensen, E. D.
Poirier, B. F.
Sethi, S.
Smart, G.
Peña, A. S.
author_facet Lim, C.
Jensen, E. D.
Poirier, B. F.
Sethi, S.
Smart, G.
Peña, A. S.
author_sort Lim, C.
collection PubMed
description PURPOSE: Systemic diseases or drugs administered early in life may cause a disruption in amelogenesis and contribute to the qualitative defect of enamel described as molar–incisor hypomineralisation (MIH). Therefore, an increase in prevalence of MIH in children with type 1 diabetes (T1D) may be expected as this systemic disorder is commonly diagnosed in early childhood. The aim of this study was to determine the prevalence of MIH in a cohort of children with T1D and investigate diagnosis of MIH with T1D factors. METHODS: Cross-sectional study of children with T1D recruited from paediatric diabetes clinics at the Women’s and Children’s Hospital (South Australia). A detailed medical history, comprehensive dental and MIH examination according to the European Academy of Paediatric Dentistry (EAPD) long form classification was collected for each child. All upper and lower first permanent molars and central incisors were scored. RESULTS: A total number of 73 participants; 35 (47.95%) males were examined including 584 teeth. The mean age of the participants was 13.25 ± 2.58 years, with a mean age of diagnosis 7.75 ± 3.58 years, and a mean HbA1c of 8.5 ± 1.6%. 42 out of 73 children (54.8%) had enamel defects on at least one of the teeth examined. However, 19.2% met the criteria for MIH. Univariate and bivariate analyses were conducted but no significant associations were noted between MIH and risk factors including diabetes control (p > 0.1). CONCLUSION: There was a high prevalence of enamel defects and MIH amongst children with T1D. More research is required to establish association between T1D and MIH.
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spelling pubmed-99922262023-03-09 Molar-incisor hypomineralisation prevalence in a cohort of Australian children with type 1 diabetes Lim, C. Jensen, E. D. Poirier, B. F. Sethi, S. Smart, G. Peña, A. S. Eur Arch Paediatr Dent Original Scientific Article PURPOSE: Systemic diseases or drugs administered early in life may cause a disruption in amelogenesis and contribute to the qualitative defect of enamel described as molar–incisor hypomineralisation (MIH). Therefore, an increase in prevalence of MIH in children with type 1 diabetes (T1D) may be expected as this systemic disorder is commonly diagnosed in early childhood. The aim of this study was to determine the prevalence of MIH in a cohort of children with T1D and investigate diagnosis of MIH with T1D factors. METHODS: Cross-sectional study of children with T1D recruited from paediatric diabetes clinics at the Women’s and Children’s Hospital (South Australia). A detailed medical history, comprehensive dental and MIH examination according to the European Academy of Paediatric Dentistry (EAPD) long form classification was collected for each child. All upper and lower first permanent molars and central incisors were scored. RESULTS: A total number of 73 participants; 35 (47.95%) males were examined including 584 teeth. The mean age of the participants was 13.25 ± 2.58 years, with a mean age of diagnosis 7.75 ± 3.58 years, and a mean HbA1c of 8.5 ± 1.6%. 42 out of 73 children (54.8%) had enamel defects on at least one of the teeth examined. However, 19.2% met the criteria for MIH. Univariate and bivariate analyses were conducted but no significant associations were noted between MIH and risk factors including diabetes control (p > 0.1). CONCLUSION: There was a high prevalence of enamel defects and MIH amongst children with T1D. More research is required to establish association between T1D and MIH. Springer Berlin Heidelberg 2022-11-08 2023 /pmc/articles/PMC9992226/ /pubmed/36348176 http://dx.doi.org/10.1007/s40368-022-00765-z Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Scientific Article
Lim, C.
Jensen, E. D.
Poirier, B. F.
Sethi, S.
Smart, G.
Peña, A. S.
Molar-incisor hypomineralisation prevalence in a cohort of Australian children with type 1 diabetes
title Molar-incisor hypomineralisation prevalence in a cohort of Australian children with type 1 diabetes
title_full Molar-incisor hypomineralisation prevalence in a cohort of Australian children with type 1 diabetes
title_fullStr Molar-incisor hypomineralisation prevalence in a cohort of Australian children with type 1 diabetes
title_full_unstemmed Molar-incisor hypomineralisation prevalence in a cohort of Australian children with type 1 diabetes
title_short Molar-incisor hypomineralisation prevalence in a cohort of Australian children with type 1 diabetes
title_sort molar-incisor hypomineralisation prevalence in a cohort of australian children with type 1 diabetes
topic Original Scientific Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992226/
https://www.ncbi.nlm.nih.gov/pubmed/36348176
http://dx.doi.org/10.1007/s40368-022-00765-z
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