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A buprenorphine depot formulation provides effective sustained post-surgical analgesia for 72 h in mouse femoral fracture models

Adequate pain management is essential for ethical and scientific reasons in animal experiments and should completely cover the period of expected pain without the need for frequent re-application. However, current depot formulations of Buprenorphine are only available in the USA and have limited dur...

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Detalles Bibliográficos
Autores principales:	Wolter, Angelique, Bucher, Christian H., Kurmies, Sebastian, Schreiner, Viktoria, Konietschke, Frank, Hohlbaum, Katharina, Klopfleisch, Robert, Löhning, Max, Thöne-Reineke, Christa, Buttgereit, Frank, Huwyler, Jörg, Jirkof, Paulin, Rapp, Anna E., Lang, Annemarie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992384/ https://www.ncbi.nlm.nih.gov/pubmed/36882427 http://dx.doi.org/10.1038/s41598-023-30641-9

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