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WFDC12-overexpressing contributes to the development of atopic dermatitis via accelerating ALOX12/15 metabolism and PAF accumulation

Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by eczema-like skin lesions, dry skin, severe itching, and recurrent recurrence. The whey acidic protein four-disulfide core domain gene WFDC12 is highly expressed in skin tissue and up-regulated in the skin lesions of AD pa...

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Detalles Bibliográficos
Autores principales:	Li, Guolin, Gu, Linna, Zhao, Fulei, Hu, Yawen, Wang, Xiaoyan, Zeng, Fanlian, Yu, Jiadong, Yue, Chengcheng, Zhou, Pei, Li, Ya, Feng, Yuting, Hu, Jing, Huang, Nongyu, Wu, Wenling, Cui, Kaijun, Li, Wei, Li, Jiong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992393/ https://www.ncbi.nlm.nih.gov/pubmed/36882395 http://dx.doi.org/10.1038/s41419-023-05686-3

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