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Flow diverters in the treatment of unruptured vertebral artery dissecting aneurysm: A single-center experience

OBJECTIVE: To evaluate the efficacy and safety of flow diverters (FD) in the treatment of vertebral artery dissecting aneurysm (VADA). METHODS: A total of 16 patients with 17 unruptured VADAs treated with FD from January 2017 to May 2021 were included. Data of clinical outcomes and radiographic exam...

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Autores principales: Lu, Xiaoyang, Zhang, Yuansheng, Zhou, Hu, Jian, Lipeng, Yin, Shi, Li, Tao, Huang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992407/
https://www.ncbi.nlm.nih.gov/pubmed/36908600
http://dx.doi.org/10.3389/fneur.2023.1050619
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author Lu, Xiaoyang
Zhang, Yuansheng
Zhou, Hu
Jian, Lipeng
Yin, Shi
Li, Tao
Huang, Wei
author_facet Lu, Xiaoyang
Zhang, Yuansheng
Zhou, Hu
Jian, Lipeng
Yin, Shi
Li, Tao
Huang, Wei
author_sort Lu, Xiaoyang
collection PubMed
description OBJECTIVE: To evaluate the efficacy and safety of flow diverters (FD) in the treatment of vertebral artery dissecting aneurysm (VADA). METHODS: A total of 16 patients with 17 unruptured VADAs treated with FD from January 2017 to May 2021 were included. Data of clinical outcomes and radiographic examination were collected and assessed by the modified Rankin Scale (mRS) and O'Kelly-Marotta (OKM) grading scale. RESULTS: All patients were treated with a single FD. No perioperative complications occurred. The mean age was 55.1 years old. The mean size of the aneurysm was 10.4 mm. All patients had a favorable occlusion (OKM D + C3) result and the complete occlusion rate in the 6th month was 66.7% (OKM D). The mean clinical follow-up time was 7.8 months, and all patients had a good clinical outcome (mRS = 0). No procedure-related complication occurred at the last follow-up time. CONCLUSION: FD is an effective and safe tool for treating unruptured VADA. Long-term prospective studies with a large sample are still needed to confirm these findings in the future.
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spelling pubmed-99924072023-03-09 Flow diverters in the treatment of unruptured vertebral artery dissecting aneurysm: A single-center experience Lu, Xiaoyang Zhang, Yuansheng Zhou, Hu Jian, Lipeng Yin, Shi Li, Tao Huang, Wei Front Neurol Neurology OBJECTIVE: To evaluate the efficacy and safety of flow diverters (FD) in the treatment of vertebral artery dissecting aneurysm (VADA). METHODS: A total of 16 patients with 17 unruptured VADAs treated with FD from January 2017 to May 2021 were included. Data of clinical outcomes and radiographic examination were collected and assessed by the modified Rankin Scale (mRS) and O'Kelly-Marotta (OKM) grading scale. RESULTS: All patients were treated with a single FD. No perioperative complications occurred. The mean age was 55.1 years old. The mean size of the aneurysm was 10.4 mm. All patients had a favorable occlusion (OKM D + C3) result and the complete occlusion rate in the 6th month was 66.7% (OKM D). The mean clinical follow-up time was 7.8 months, and all patients had a good clinical outcome (mRS = 0). No procedure-related complication occurred at the last follow-up time. CONCLUSION: FD is an effective and safe tool for treating unruptured VADA. Long-term prospective studies with a large sample are still needed to confirm these findings in the future. Frontiers Media S.A. 2023-02-22 /pmc/articles/PMC9992407/ /pubmed/36908600 http://dx.doi.org/10.3389/fneur.2023.1050619 Text en Copyright © 2023 Lu, Zhang, Zhou, Jian, Yin, Li and Huang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Lu, Xiaoyang
Zhang, Yuansheng
Zhou, Hu
Jian, Lipeng
Yin, Shi
Li, Tao
Huang, Wei
Flow diverters in the treatment of unruptured vertebral artery dissecting aneurysm: A single-center experience
title Flow diverters in the treatment of unruptured vertebral artery dissecting aneurysm: A single-center experience
title_full Flow diverters in the treatment of unruptured vertebral artery dissecting aneurysm: A single-center experience
title_fullStr Flow diverters in the treatment of unruptured vertebral artery dissecting aneurysm: A single-center experience
title_full_unstemmed Flow diverters in the treatment of unruptured vertebral artery dissecting aneurysm: A single-center experience
title_short Flow diverters in the treatment of unruptured vertebral artery dissecting aneurysm: A single-center experience
title_sort flow diverters in the treatment of unruptured vertebral artery dissecting aneurysm: a single-center experience
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992407/
https://www.ncbi.nlm.nih.gov/pubmed/36908600
http://dx.doi.org/10.3389/fneur.2023.1050619
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