SOX11 regulates SWI/SNF complex components as member of the adrenergic neuroblastoma core regulatory circuitry

The pediatric extra-cranial tumor neuroblastoma displays a low mutational burden while recurrent copy number alterations are present in most high-risk cases. Here, we identify SOX11 as a dependency transcription factor in adrenergic neuroblastoma based on recurrent chromosome 2p focal gains and ampl...

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Detalles Bibliográficos
Autores principales: Decaesteker, Bieke, Louwagie, Amber, Loontiens, Siebe, De Vloed, Fanny, Bekaert, Sarah-Lee, Roels, Juliette, Vanhauwaert, Suzanne, De Brouwer, Sara, Sanders, Ellen, Berezovskaya, Alla, Denecker, Geertrui, D’haene, Eva, Van Haver, Stéphane, Van Loocke, Wouter, Van Dorpe, Jo, Creytens, David, Van Roy, Nadine, Pieters, Tim, Van Neste, Christophe, Fischer, Matthias, Van Vlierberghe, Pieter, Roberts, Stephen S., Schulte, Johannes, Ek, Sara, Versteeg, Rogier, Koster, Jan, van Nes, Johan, Zimmerman, Mark, De Preter, Katleen, Speleman, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992472/
https://www.ncbi.nlm.nih.gov/pubmed/36882421
http://dx.doi.org/10.1038/s41467-023-36735-2

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