Cargando…

Drug_SNSMiner: standard pharmacovigilance pipeline for detection of adverse drug reaction using SNS data

As society continues to age, it is becoming increasingly important to monitor drug use in the elderly. Social media data have been used for monitoring adverse drug reactions. The aim of this study was to determine whether social network studies (SNS) are useful sources of drug side effects informati...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Seunghee, Woo, Hyekyung, Lee, Chung Chun, Kim, Gyeongmin, Kim, Jong-Yeup, Lee, Suehyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992476/
https://www.ncbi.nlm.nih.gov/pubmed/36882478
http://dx.doi.org/10.1038/s41598-023-28912-6
_version_ 1784902318128365568
author Lee, Seunghee
Woo, Hyekyung
Lee, Chung Chun
Kim, Gyeongmin
Kim, Jong-Yeup
Lee, Suehyun
author_facet Lee, Seunghee
Woo, Hyekyung
Lee, Chung Chun
Kim, Gyeongmin
Kim, Jong-Yeup
Lee, Suehyun
author_sort Lee, Seunghee
collection PubMed
description As society continues to age, it is becoming increasingly important to monitor drug use in the elderly. Social media data have been used for monitoring adverse drug reactions. The aim of this study was to determine whether social network studies (SNS) are useful sources of drug side effects information. We propose a method for utilizing SNS data to plot the known side effects of geriatric drugs in a dosing map. We developed a lexicon of drug terms associated with side effects and mapped patterns from social media data. We confirmed that well-known side effects may be obtained by utilizing SNS data. Based on these results, we propose a pharmacovigilance pipeline that can be extended to unknown side effects. We propose the standard analysis pipeline Drug_SNSMiner for monitoring side effects using SNS data and evaluated it as a drug prescription platform for the elderly. We confirmed that side effects may be monitored from the consumer’s perspective based on SNS data using only drug information. SNS data were deemed good sources of information to determine ADRs and obtain other complementary data. We established that these learning data are invaluable for AI requiring the acquisition of ADR posts on efficacious drugs.
format Online
Article
Text
id pubmed-9992476
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-99924762023-03-09 Drug_SNSMiner: standard pharmacovigilance pipeline for detection of adverse drug reaction using SNS data Lee, Seunghee Woo, Hyekyung Lee, Chung Chun Kim, Gyeongmin Kim, Jong-Yeup Lee, Suehyun Sci Rep Article As society continues to age, it is becoming increasingly important to monitor drug use in the elderly. Social media data have been used for monitoring adverse drug reactions. The aim of this study was to determine whether social network studies (SNS) are useful sources of drug side effects information. We propose a method for utilizing SNS data to plot the known side effects of geriatric drugs in a dosing map. We developed a lexicon of drug terms associated with side effects and mapped patterns from social media data. We confirmed that well-known side effects may be obtained by utilizing SNS data. Based on these results, we propose a pharmacovigilance pipeline that can be extended to unknown side effects. We propose the standard analysis pipeline Drug_SNSMiner for monitoring side effects using SNS data and evaluated it as a drug prescription platform for the elderly. We confirmed that side effects may be monitored from the consumer’s perspective based on SNS data using only drug information. SNS data were deemed good sources of information to determine ADRs and obtain other complementary data. We established that these learning data are invaluable for AI requiring the acquisition of ADR posts on efficacious drugs. Nature Publishing Group UK 2023-03-07 /pmc/articles/PMC9992476/ /pubmed/36882478 http://dx.doi.org/10.1038/s41598-023-28912-6 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Lee, Seunghee
Woo, Hyekyung
Lee, Chung Chun
Kim, Gyeongmin
Kim, Jong-Yeup
Lee, Suehyun
Drug_SNSMiner: standard pharmacovigilance pipeline for detection of adverse drug reaction using SNS data
title Drug_SNSMiner: standard pharmacovigilance pipeline for detection of adverse drug reaction using SNS data
title_full Drug_SNSMiner: standard pharmacovigilance pipeline for detection of adverse drug reaction using SNS data
title_fullStr Drug_SNSMiner: standard pharmacovigilance pipeline for detection of adverse drug reaction using SNS data
title_full_unstemmed Drug_SNSMiner: standard pharmacovigilance pipeline for detection of adverse drug reaction using SNS data
title_short Drug_SNSMiner: standard pharmacovigilance pipeline for detection of adverse drug reaction using SNS data
title_sort drug_snsminer: standard pharmacovigilance pipeline for detection of adverse drug reaction using sns data
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992476/
https://www.ncbi.nlm.nih.gov/pubmed/36882478
http://dx.doi.org/10.1038/s41598-023-28912-6
work_keys_str_mv AT leeseunghee drugsnsminerstandardpharmacovigilancepipelinefordetectionofadversedrugreactionusingsnsdata
AT woohyekyung drugsnsminerstandardpharmacovigilancepipelinefordetectionofadversedrugreactionusingsnsdata
AT leechungchun drugsnsminerstandardpharmacovigilancepipelinefordetectionofadversedrugreactionusingsnsdata
AT kimgyeongmin drugsnsminerstandardpharmacovigilancepipelinefordetectionofadversedrugreactionusingsnsdata
AT kimjongyeup drugsnsminerstandardpharmacovigilancepipelinefordetectionofadversedrugreactionusingsnsdata
AT leesuehyun drugsnsminerstandardpharmacovigilancepipelinefordetectionofadversedrugreactionusingsnsdata