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The lack of keratinized mucosa as a risk factor for peri-implantitis: a systematic review and meta-analysis
This study aimed to investigate the effect of the lack of keratinized mucosa on the risk of peri-implantitis, while also accounting for possible confounding factors. A literature search was conducted in PubMed and Scopus, including human studies that assessed the presence and width of keratinized mu...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992510/ https://www.ncbi.nlm.nih.gov/pubmed/36882495 http://dx.doi.org/10.1038/s41598-023-30890-8 |
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author | Mahardawi, Basel Jiaranuchart, Sirimanas Damrongsirirat, Napat Arunjaroensuk, Sirida Mattheos, Nikos Somboonsavatdee, Anupap Pimkhaokham, Atiphan |
author_facet | Mahardawi, Basel Jiaranuchart, Sirimanas Damrongsirirat, Napat Arunjaroensuk, Sirida Mattheos, Nikos Somboonsavatdee, Anupap Pimkhaokham, Atiphan |
author_sort | Mahardawi, Basel |
collection | PubMed |
description | This study aimed to investigate the effect of the lack of keratinized mucosa on the risk of peri-implantitis, while also accounting for possible confounding factors. A literature search was conducted in PubMed and Scopus, including human studies that assessed the presence and width of keratinized mucosa in relation to the occurrence of peri-implantitis. Twenty-two articles were included, and 16 cross-sectional studies we meta-analyzed. The prevalence of peri-implantitis was 6.68–62.3% on patient-level and 4.5–58.1% on implant-level. The overall analysis indicated that the lack of keratinized mucosa was associated with a higher prevalence of peri-implantitis (OR = 2.78, 95% CI 2.07–3.74, p < 0.00001). Similar results were shown when subgroup analyses were performed, including studies with a similar case definition of peri-implantitis (Marginal Bone Loss, MBL ≥ 2 mm) (OR = 1.96, 95% CI 1.41–2.73, p < 0.0001), fixed prostheses only (OR = 2.82, 95% CI 1.85–4.28, p < 0.00001), patients under regular implant maintenance (OR = 2.08, 95% CI 1.41–3.08, p = 0.0002), and studies adjusting for other variables (OR = 3.68, 95% CI 2.32–5.82, p = 0.007). Thus, the lack of keratinized mucosa is a risk factor that increases the prevalence of peri-implantitis and should be accounted for when placing dental implants. |
format | Online Article Text |
id | pubmed-9992510 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-99925102023-03-09 The lack of keratinized mucosa as a risk factor for peri-implantitis: a systematic review and meta-analysis Mahardawi, Basel Jiaranuchart, Sirimanas Damrongsirirat, Napat Arunjaroensuk, Sirida Mattheos, Nikos Somboonsavatdee, Anupap Pimkhaokham, Atiphan Sci Rep Article This study aimed to investigate the effect of the lack of keratinized mucosa on the risk of peri-implantitis, while also accounting for possible confounding factors. A literature search was conducted in PubMed and Scopus, including human studies that assessed the presence and width of keratinized mucosa in relation to the occurrence of peri-implantitis. Twenty-two articles were included, and 16 cross-sectional studies we meta-analyzed. The prevalence of peri-implantitis was 6.68–62.3% on patient-level and 4.5–58.1% on implant-level. The overall analysis indicated that the lack of keratinized mucosa was associated with a higher prevalence of peri-implantitis (OR = 2.78, 95% CI 2.07–3.74, p < 0.00001). Similar results were shown when subgroup analyses were performed, including studies with a similar case definition of peri-implantitis (Marginal Bone Loss, MBL ≥ 2 mm) (OR = 1.96, 95% CI 1.41–2.73, p < 0.0001), fixed prostheses only (OR = 2.82, 95% CI 1.85–4.28, p < 0.00001), patients under regular implant maintenance (OR = 2.08, 95% CI 1.41–3.08, p = 0.0002), and studies adjusting for other variables (OR = 3.68, 95% CI 2.32–5.82, p = 0.007). Thus, the lack of keratinized mucosa is a risk factor that increases the prevalence of peri-implantitis and should be accounted for when placing dental implants. Nature Publishing Group UK 2023-03-07 /pmc/articles/PMC9992510/ /pubmed/36882495 http://dx.doi.org/10.1038/s41598-023-30890-8 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Mahardawi, Basel Jiaranuchart, Sirimanas Damrongsirirat, Napat Arunjaroensuk, Sirida Mattheos, Nikos Somboonsavatdee, Anupap Pimkhaokham, Atiphan The lack of keratinized mucosa as a risk factor for peri-implantitis: a systematic review and meta-analysis |
title | The lack of keratinized mucosa as a risk factor for peri-implantitis: a systematic review and meta-analysis |
title_full | The lack of keratinized mucosa as a risk factor for peri-implantitis: a systematic review and meta-analysis |
title_fullStr | The lack of keratinized mucosa as a risk factor for peri-implantitis: a systematic review and meta-analysis |
title_full_unstemmed | The lack of keratinized mucosa as a risk factor for peri-implantitis: a systematic review and meta-analysis |
title_short | The lack of keratinized mucosa as a risk factor for peri-implantitis: a systematic review and meta-analysis |
title_sort | lack of keratinized mucosa as a risk factor for peri-implantitis: a systematic review and meta-analysis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992510/ https://www.ncbi.nlm.nih.gov/pubmed/36882495 http://dx.doi.org/10.1038/s41598-023-30890-8 |
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